Incredibly cool thing. Open to correction by immunologists etc; this is a lay understanding of the literature. But here goes:
My #MultipleSclerosis treatment depletes B-cells.
B-cells are largely responsible for releasing IgE.
IgE is a big mediator of allergic response.
My hayfever has disappeared.
I have to do my #MultipleSclerosis infusion today, steroids included, and I’m already pissed and exhausted from stupid JBLM bombing for hours two straight nights in a row. #PNWlife
Groundbreaking research reveals MS patients show distinctive medical patterns up to 20 years before diagnosis, offering potential for earlier intervention and improved patient outcomes. #MultipleSclerosis #Healthcare
damn summer is hard
It's that time again, but least I have my Dunks. That's the important part. 
#Introduction Hashtags, so I can pin this post and take them out of my profile:
#Education #Research #Phd, #BCS #Computing #Teacher #CCT
#CSEd #Programming #BCS
#ActuallyAutistic
#ActuallyADHD
I live with #MultipleSclerosis
#Zen / #Nonduality #Buddhist, weirdly into #Jung
#Research topics:
- #EdAI / #AIEd - #LLMs in #Education
- #CriticalStudies of #EdTech
- #Neurodiversity in #Education, and the experience of ND educators.
2025. Chorzy na stwardnienie rozsiane, zdiagnozowani po 2010 praktycznie nie lądują na wózkach. Leków jest kilkanaście, wdrożone odpowiednio wcześnie powodują, że choroba staje się przewlekle akceptowalna. Trzeba pamiętać o lekach, czasami robić sobie zastrzyki, regularnie meldować się na kontrole i odbiory leków, ale żyje się NORMALNIE. Praca, sport, dzieci. Jeśli nie powiem komuś że mam SM (tu mem z pękającym pryszczersem), to nikt nie będzie wiedział. Bba, jestem w tak głębokiej remisji, że jeśli pójdę w dobrej formie do obcego neurologa, to w badaniu fizykalnym może nie wybadać, wsypie mnie tylko MRI.
I nie jest jakimś szczególnym odkryciem, że wszystko to dzięki wdrożonemu wcześnie, agresywnemu, systematycznemu leczeniu.
Dlaczego więc ciągle na grupach dla chorych czytam "Czy są tutaj osoby, które świadomie NIE zdecydowały się na leczenie?" i odpowiedzi w stylu "tylko natura, spróbuj ziół, homeopatia działa".
To te same osoby, które za 10 lat będą u tych samych znachorów szukały metod na wstanie z (refundowanego) wózka inwalidzkiego i narzekały, że im lekarze nie pomogli.
To jak w tym szmoncesie o rabinie, loterii i Bogu. Pomogliby, gdybyście, debile, dali im szansę!
Is your brain running out of power? Scientists uncover why MS slowly breaks our motor control — and how to fight back. #MultipleSclerosis #Neuroscience #MedicalBreakthrough
https://geekoo.news/your-balance-depends-on-this-tiny-cells-power-supply/
Mind in the mist: the interplay between fatigue, information processing and brain fog
https://www.tandfonline.com/doi/full/10.1080/21641846.2025.2513194
Image is from the latest Science for ME weekly update
@mecfs
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME @longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#brainfog #MultipleSclerosis @multiplesclerosis
I’ve just gone through pre-screening for the Octopus Trial into progressive #MultipleSclerosis that is finally starting at the QMC in Nottingham. Next screen for suitability is in-person on Monday. Fingers crossed. Apart from what the drugs may do to slow my #MS progression, the real prize is the close supervision of the MS team that I sadly don’t get regularly enough at the moment (and I’ll still get even if I’m on a placebo arm of the trial).
Action observation combined with motor imagery of the upper extremities for people with multiple sclerosis
Nice skeptic article as any true science should be. Anything that links the 2011 Russo paper "Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects" is to be celebrated. Here is the link again in case somebody missed it.
https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01238.x
Russo's paper has been cited 1,161 times and it deals with exogenous cannabinoids and terpenes synergy, not just endogenous o made inside our body, as did the original 1998 Mechoulam research.
Indeed, due to obsolete prohibitionism and sad profit-comes-first mentality, the current cannabis and hemp markets are a wild west of fake adultered product and unproven claims.
Yet since 2011 hundreds of studies have confirmed the entourage effect. Here is a small and incomplete collection of full spectrum extract papers 2004-2023.
https://www.cvresearch.info/full-spectrum-hemp-extracts-studies
OPs article calls for more standarized extract testing, even though Big Pharmas really prefers patentable, cheap to make, single molecule, symptom masking drugs. Good luck with that.
I agree with the article bottomline: governments should step up to the research task instead of trusting this critical matter to profit-driven corporations. Mixed isolate cannabis pharmaceuticals have been in the market for over a decade and proven their capabilities and limitations.
That is the case of Sativex, a 700 US$ 1:1 (thc:cbd) oral spray that controls some symptoms of MS yet fails to work for other conditions. Three separate studies ( Israeli, Brazilian and American) have since proven that full flower artisanal extracts are up to 6x more effective than expensive isolate preparations like Sativex
https://sensiseeds-com.translate.goog/es/blog/sativex-el-pionero-de-los-farmacos-derivados-del-cannabis/?_x_tr_sl=auto&_x_tr_tl=en&_x_tr_hl=es-419&_x_tr_pto=wapp
#Cannabis #cannabismedicinal #thc #thca #cbd #cbda #entourageeffect
#cannabislegal #Cannabisgesetz
#cannabislegalisierung #ganja
#maconha #weed #cannabisculture
#cannabisresearch #chronicillness
#ptsd #arthritis #stress #depression
#multiplesclerosis #ImmuneSystem
It’s infusion day again. Let’s get this done. #Tysabri #MultipleSclerosis #ms
Hey peeps, got a little time to assist in some research? add your voice.
I've previously completed a survey and have confirmed with James and Melanie that it's OK to share on Mastodon.
Boosts appreciated.
#autoimmune #lupus #flare #IBD #RheumatoidArthritis #mctd #uctd #sjogrens #SystemicSclerosis #PolymyalgiaRheumatica #MultipleSclerosis #ThyroidDisease #AutoimmuneEncephalitis #AntiphospholipidSyndrome #Type1Diabetes
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We’re now conducting a new survey, 'INSPIRE-Flare', to build
Today is officially my 10 year #MultipleSclerosis diagnosis anniversary! I went to Disneyland earlier this month to celebrate, but I wanted to acknowledge the day.
Multiple Sclerosis For Dummies by Rosalind Kalb, 2025
Multiple Sclerosis For Dummies helps you and your loved ones understand the importance of early treatment and become familiar with all of the latest treatment options and therapies.
In a twin study, Max Planck researchers successfully characterized gut bacteria involved in multiple sclerosis and provided evidence of their pathogenicity.
https://www.mpg.de/24685137/0507-psy-multiple-sclerosis-triggers-in-the-gut-flora-155111-x #MultipleSclerosis
https://www.europesays.com/2073142/ Estrogen-related receptors could be a key to repairing energy metabolism and muscle fatigue #Aging #brain #cancer #Cell #CellMetabolism #Dementia #Energy #Estrogen #exercise #fatigue #Food #genes #Heart #HeartDisease #hormone #MetabolicDisorders #Metabolism #Mitochondria #MultipleSclerosis #Muscle #Receptor #research #Sclerosis
This week Christina Applegate and Jamie-Lynn Sigler promoted their podcast (https://www.messythepodcast.com) and general MS/Chronic Illness/Disability advocacy on Conan O’Brien’s podcast (https://teamcoco.com/podcasts/conan-obrien-needs-a-friend/episodes/christina-applegate-and-jamie-lynn-sigler) with Christina joining in “Work from Bed”-style
#MusComEnt #WorldMSDay #Disability #MultipleSclerosis #ChristinaApplegate #JamieLynnSigler
During the filming of “Dead to Me” in 2018 Christina Applegate began to experience symptoms that were later diagnosed as #MultipleSclerosis in early 2021. She went public with her diagnosis later that year. She has since retired from acting due to MS but now has a wonderful podcast with fellow MS-diagnosed actress Jamie-Lynn Sigler (https://www.messythepodcast.com)
#MusComEnt #WorldMSDay #DontTellMomTheBabysittersDead
#ChristinaAppleGate #JamieLynnSigler
