Sunday fun day in Druids Glen making some low protein sweet and savoury
#PKU #Metabolic #Sauerkraut #Toasties #Muffins #Ireland
Sunday fun day in Druids Glen making some low protein sweet and savoury
#PKU #Metabolic #Sauerkraut #Toasties #Muffins #Ireland
Niche-targeting of #antimicrobials. @EmmaGlass33 @papinsysbio &co use a computational data-driven approach to #DrugTarget discovery by identifying #metabolic signatures of diverse #pathogens conserved within body sites. Proof-of-principle with stomach-specific pathogens #PLOSBiology https://plos.io/40TewzH
#Navajo #uranium miners, people #downwind of atom bomb tests demand justice as Congress lets aid program lapse
by Keetra Bippus / Cronkite News
July 5, 2024
WASHINGTON – "A federal program to compensate people exposed to fallout from U.S. nuclear testing expired June 10.
"The #Radiation Exposure Compensation Act has paid out $2.6 billion to over 41,000 people since 1992. In March, the U.S. Justice Department projected that another 1,070 claims would be approved by the end of September.
“'Why do we have to beg to pass #RECA?' said #MaggieBilliman, whose father, a #NavajoCodeTalker during World War II, died of stomach cancer she attributes to exposure to #fallout that affected their hometown in #Arizona. 'You don’t put a price tag on human life.'
"Starting with the #ManhattanProject’s Trinity test on July 16, 1945, weeks before bombs destroyed #Hiroshima and #Nagasaki, the U.S. government conducted 94 tests that produced radioactive mushroom clouds in remote areas of the West. Most were over #Nevada. One was over #NewMexico.
"People #downwind – including many in #Arizona – were exposed to dangerous #fallout, typically without warning.
"The Billimans’ hometown, #SawmillArizona, on #NavajoLand, is part of the large affected area where Congress made residents eligible for compensation.
"#Radioactive particles fell throughout Arizona, according to research from Princeton University’s Program on Science and Global Security. The state’s population grew from about half a million just before World War II to over 1.3 million in the early 1960s.
"Congress adopted RECA in 1992 to address claims from downwinders and uranium miners.
"The program offers an apology, and lump sum compensation ranging from $50,000 to $100,000 to those who developed certain illnesses linked with radiation exposure, and who either lived in the #FalloutZones or worked at #UraniumMines and #UraniumMills.
"The law came in response to lawsuits from uranium workers who accused the government of failing to warn them about radiation hazards.
From 1944 to 1986, nearly 30 million tons of uranium ore was extracted from Navajo lands. The Manhattan Project itself, led by physicist #RobertOppenheimer, was disbanded in 1947, two years after Japan surrendered to end World War II.
"An estimated 3,000 to 5,000 Navajo people worked in the mines. They and their families lived nearby.
“'The closer you live to mine waste, the higher your risk of chronic #metabolic disease,' said Chris Shuey, director of the Uranium Impact Assessment Program at the Southwest Research and Information Center, a nonprofit research and advocacy group. 'People who live in these communities next to these wastes, they’re exposed through all of the pathways: air, water, land.'
"Claims from Arizona, New Mexico, Utah and #Colorado account for $1.8 billion of the payouts under RECA.
"Most of the #NavajoNation was covered due to potential fallout. About one in seven approved claims – 5,480 through the end of 2023 – have come from #NativeAmericans, 86% of them Navajo, totalling $372.6 million.
"The Environmental Protection Agency counts 523 abandoned uranium mines on or near the Navajo reservation that spans Arizona, New Mexico and Utah, an area bigger than Massachusetts, New Hampshire and Vermont combined.
"The Senate voted 69-31 in March to extend the RECA filing period for five more years, with 46 Democrats and 20 Republicans in favor, along with Sen. #KrystenSinema of Arizona and two other independents. Sen. #MarkKelly, D-Ariz., also supported the bill.
The bill has stalled in the House, with no explanation from Speaker Mike Johnson or Majority Leader Steve Scalise, both Republicans from Louisiana.
"Their aides did not respond to multiple requests for comment."
I’m out southside this morning with an event for kids from the Temple Street Hospital Metabolic Clinic. #PKU #CHITempleStreet #TempleStreet #Metabolic #Mastodaoine #Sunday #Trees. #Dublin
Brain Acidity Linked With Multiple Neurological Disorders
https://www.sciencealert.com/brain-acidity-linked-with-multiple-neurological-disorders #psychology #BrainAcidity #Neurological #Disorders #metabolic #dysfunction #lactate #pH
"Chemicals in #plastic food and drink packaging can act like or interfere with our body’s natural #hormones, possibly leading to a slew of health issues, including #metabolic disorders.
Not all plastics are created equal. Some, like polyurethane (PUR), polyvinyl chloride (PVC), and low-density polyethylene (LDPE) – commonly used in everyday items such as cling wrap and Ziploc bags – were found to have more profound effects on cell nuclei than others."
The gut #microbiome interacts with the loss of female #sex #hormones to exacerbate #metabolic disease, including weight gain, fat in the #liver and the expression of #genes linked with inflammation, researchers found in a new rodent study. The findings may shed light on why #women are at significantly greater risk of metabolic diseases such as #obesity and Type 2 #diabetes after #menopause
#Microbiology #Biology #Medical #sflorg
https://www.sflorg.com/2024/02/mcb02222401.html
Your Body Has a Built-in Weight Loss System You May Not Know About
https://www.sciencealert.com/your-body-has-a-built-in-weight-loss-system-you-may-not-know-about #WeightLoss #metabolic #disease #incretin #hormones #gut #ColonicBrake
#Plants have evolved fiendishly complicated #metabolic networks. For years, scientists focused on how plants make secondary #metabolites, the compounds that plants produce to enhance their defense and survival mechanisms.
#Biology #Chemistry #sflorg
https://www.sflorg.com/2023/12/bio12182301.html
An early phase in the process of developing #Alzheimer’s disease is a #metabolic increase in a part of the #brain called the #hippocampus, report researchers from Karolinska Institutet
#Psychiatry #Neuroscience #sflorg
https://www.sflorg.com/2023/11/psyc11012301.html
New #BehindThePaper post up on the PLOS #Biologue.
@OlgaPonomarova discusses how testing many diverse hypothesis brought them to find the relationship between apparently unrelated #metabolic pathways.
Check out the paper here: https://plos.io/41r41k4
Researchers at the Faculty of Medicine at the University of Freiburg have gained significant new insights into #metabolic processes in the #kidney.
#Biology #sflorg
https://www.sflorg.com/2023/06/bio06052301.html
#Plastics, which are now ubiquitous, contain #endocrine disrupting #chemicals, or #EDCs, that have been linked to increased risk of many chronic #diseases; parental exposure to EDCs, for example, has been shown to cause #metabolic disorders, including #obesity and #diabetes, in the offspring.
#Environmental #Medical #sflorg
https://www.sflorg.com/2023/01/en01122302.html