shakedown.social is one of the many independent Mastodon servers you can use to participate in the fediverse.
A community for live music fans with roots in the jam scene. Shakedown Social is run by a team of volunteers (led by @clifff and @sethadam1) and funded by donations.

Administered by:

Server stats:

248
active users

#Cannabinoids

0 posts0 participants0 posts today

ENG: "Over 70% Of Studies Back Medical Cannabis In Cancer Treatment, Meta-Analysis Finds." They searched 10.000 published papers. Keep that in mind, next time you read the old " more reasearch is needed".

Will gladly share a proven protocol in comments if requested. Nothing for sale. Strictly educational purposes to correct such rampant intentional misinformation.

forbes.com/sites/dariosabaghi/

ESP: "Meta análisis de 10.000 estudios científicos publicados reveló una tendencia significativa ( 71.4%) que apoya el potencial terapéutico del cannabis, en particular para el manejo de los síntomas relacionados con el cáncer y efectos anticancerígenos directos."

Con gusto aclaro dudas sobre cómo usarlo para este fin. Solo pregunten en comentarios. No se vende nada, el fin es educativo para contrarrestar tanta desinformación intencional.

Enlace autotraducido:
www-forbes-com.translate.goog/

#cancer #Cannabinoids #medicine
#marijuana #cannabismedicinal
#medicalcannabis #healing #cbda #chemotherapy #cbd #quimioterapia
#thc #thca #regenerativemedicine
#herbalist #healthare #healthscience
#medical #marijuananews #cbn #homeostasis #chemo #pharmagreed
#endocannabinoidsystem #weed
#endocannabinoide #marihuana
#pharma #pharmaceuticals #healthcare #HealthCrisis #health

Edited for hashtags

youtube.com/shorts/mi7cS5z2cJY

ENG: Observational study on medical #cannabis use for 300 people over 50 proves medical #weed effectiveness. Patients favor high CBD low THC oral dosing ( balanced 1:1), to reduce arthritic/chronic pain and help sleep without having to chain smoke/vape. If CBD dominantes there is almost no psychotropic effect.

ESP: Ciencia moderna confirma que #marijuana medicinal alivia dolor crónico, artrítis y sueño. Estudio con 300 personas de más de 50 años revela que pacientes prefieren gotas o comestibles altos en CBD y bajos en THC. Extracto 1:1 de flor resulta aún más efectivo y evita tener que fumar/vapear para sostener efectos analgésicos/ansiolíticos. De dominar el CBD el efecto psicotropico es nulo o mínimo.

#memercredi #viernesdememes #humour #funny #humor #salud #regenerativemedicine #humornegro
#HumourNoir #science #health
#chronicillness #ChronicPainMemes
#chronicpain #thc #cbd #cbn #thca
#sleep #arthritis #cannabinoids
#cannabismedicinal #cannabismedical

ALT-TXT: Monochrome photo of old indigenous woman holding a huge joint between her swollen fingers. Text: SIGNS OF AGING: Swollen Joints

Replied in thread

@verdantsquare ask him please 😎

#Neurobiology and #Cannabinoids
This episode is about #neurobiology and cannabinoids, the compounds in #cannabis. We talk to Dr. #DanielePiomelli, a neurobiology professor at UC Irvine, and Dr. #FranjoGrotenhermen, a cannabis physician and researcher.

We learn how cannabinoids affect the #brain's #endocannabinoidsystem, which controls many functions and #health.

Join us to find out the latest facts and debates in this exciting field. cannabis-med.org/de/cannabis-t

Continued thread

"#CarlSagan, the astronomer & science communicator, speculated that #cannabis might be the 1st ever domesticated plant, the one that drove the dawn of #agriculture. The #endocannabinoid system, that regulates other systems in the human body, is where #Cannabinoids like #THC fit like a lock & a key. This is how foundational a relationship can get… you have to love that plant a whole lot to create agriculture simply to have a steady supply."
pca.st/wjj3qblb?t=20m8s

Pocket CastsA Blunt Conversation about Cannabis w/ David Bienenstock - UpstreamConversations and audio documentaries exploring a wide variety of themes pertaining to economics and politics, hosted by Della Z Duncan and Robert R. Raymond

#Cannabinoids as novel #AntiInflammatory drugs

by Prakash Nagarkatti, et al.
October, 2009

Abstract:

"Cannabinoids are a group of compounds that mediate their effects through cannabinoid receptors. The discovery of Δ9-tetrahydrocannabinol (#THC) as the major psychoactive principle in marijuana, as well as the identification of #cannabinoid receptors and their endogenous ligands, has led to a significant growth in research aimed at understanding the physiological functions of cannabinoids. Cannabinoid receptors include CB1, which is predominantly expressed in the brain, and CB2, which is primarily found on the cells of the immune system. The fact that both CB1 and CB2 receptors have been found on #immune cells suggests that cannabinoids play an important role in the regulation of the immune system. Recent studies demonstrated that administration of THC into mice triggered marked apoptosis in T cells and dendritic cells, resulting in immunosuppression. In addition, several studies showed that cannabinoids downregulate #cytokine and chemokine production and, in some models, upregulate T-regulatory cells (Tregs) as a mechanism to suppress #inflammatory responses. The #endocannabinoid system is also involved in #immunoregulation. For example, administration of endocannabinoids or use of inhibitors of enzymes that break down the endocannabinoids, led to immunosuppression and recovery from immune-mediated injury to organs such as the liver. Manipulation of endocannabinoids and/or use of exogenous cannabinoids in vivo can constitute a potent treatment modality against inflammatory disorders. This review will focus on the potential use of cannabinoids as a new class of anti-inflammatory agents against a number of inflammatory and autoimmune diseases that are primarily triggered by activated T cells or other cellular immune components."

Executive summary

- Cannabinoids, the active components of #CannabisSativa, and endogenous cannabinoids mediate their effects through activation of specific cannabinoid receptors known as cannabinoid receptor 1 and 2 (CB1 and CB2).

- The cannabinoid system has been shown both in vivo and in vitro to be involved in regulating the immune system through its immunomodulatory properties.

- Cannabinoids suppress inflammatory response and subsequently attenuate disease symptoms. This property of cannabinoids is mediated through multiple pathways such as induction of apoptosis in activated immune cells, suppression of cytokines and chemokines at inflammatory sites and upregulation of FoxP3+ regulatory T cells.

- Cannabinoids have been tested in several experimental models of autoimmune disorders such as #MultipleSclerosis, #RheumatoidArthritis, #colitis and #hepatitis and have been shown to protect the host from the pathogenesis through induction of multiple anti-inflammatory pathways.

- Cannabinoids may also be beneficial in certain types of #cancers that are triggered by #ChronicInflammation In such instances, cannabinoids can either directly inhibit tumor growth or suppress inflammation and tumor angiogenesis.

ncbi.nlm.nih.gov/pmc/articles/

PubMed Central (PMC)Cannabinoids as novel anti-inflammatory drugsCannabinoids are a group of compounds that mediate their effects through cannabinoid receptors. The discovery of Δ[9] -tetrahydrocannabinol (THC) as the major psychoactive principle in marijuana, as well as the identification of cannabinoid receptors ...

( hoping a late #introduction is better than none
at all! )

Hi everyone,

I'm Sarah, a #chemistry prof at Hanover College in Indiana. My PhD work was in #membrane #protein #massspectrometry and now I've got a special interest in anything #neuro related! I teach an entire course on the biochemistry of psychoactive drugs and I'm still trying to get into research in that field because its super interesting to me! In the mean time I'm doing some #lcms of #cannabinoids and focusing on teaching.

Yesterday, I met my orthopedic surgeon @ #UWMedical, #Seattle. I told him I use edible #cannabinoids for pain management. He was 100% supportive of them AND my compounded #HRT for pain. “Yes!” he said to HRT’s pain relieving powers for arthritis. “They work!”. After telling him my physical therapist’s office no longer requires masks he sent me to a UW PT facility where masking is required. Note: masking is required in all UW Medical facilities. #Arthritis #PainManagement #MaskUp #CovidIsNotOver