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#nucleus
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Selective macroautophagy of the #EndoplasmicReticulum (ER) and the #nucleus, known as ER-phagy and nucleophagy respectively, are poorly understood. A study in #FissionYeast reveals that conserved ER-shaping protein Yep1 (REEP1-4 ortholog) is required for these processes; in its absence, #ERphagy/#nucleophagy cargo structures accumulate in the cytoplasm #PLOSBiology https://plos.io/464ZfuI
Human #cells shield their #genetic material inside the cell #nucleus, protected by the nuclear membrane. As the control center of the cell, the nucleus must be able to exchange important messenger #molecules, metabolites or #proteins with the rest of the cell.
#Biology #sflorg
https://www.sflorg.com/2023/04/bio04272301.html
www.sflorg.comHow wiggly spaghetti guard the genomeDynamic network of proteins in the pores of the nuclear envelope blocks dangerous invaders
#Cells migrate to different tissues for a variety of reasons, including #organ development, #tissue repair and the spread of #cancer. Researchers in the McKelvey School of Engineering at Washington University in St. Louis has found unexpected activity in the #nucleus of healthy cells that provides new insight into cell mechanics.
#Biology #sflorg
https://www.sflorg.com/2023/02/bio02222301.html
www.sflorg.comCells take on dual identities with competing factors trapped in the nucleusCells migrate to different tissues for a variety of reasons
#introduction:
We are a new cell systems biology team at the #UniversityOfManchester #UoM.
We study #CellAdhesion #networks in health and disease, especially #cancer.
Fascinated by how adhesion proteins help #cells function in so many ways!