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#pathogenic

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Researchers at Univ Suffolk say "a reservoir of disease" is being created after discovering #bacteria naturally occur in #rivers are becoming resistant to #antibiotics due to the impact of #sewage. The university's team has isolated and analysed 500 strains of bacteria and found significant levels of #antibioticresistance.
"We're needlessly adding #pathogenic and virulence genes to bacteria found in the environment, and that could be creating a reservoir of #disease."
bbc.com/news/articles/cw4yx3wv

New #MysteryFungi Species Spark Disease Warning

Story by Jess Thomson, February 26, 2024

Several new species of fungus have been found lurking in waterways, and they might be harmful to humans.

The new species were discovered in the sediment of riverbeds across #Spain. Many are closely related to species of #pathogenic fungi that cause infection in humans, according to a new paper in the Journal of Fungi.

The paper notes that these types of fungus that grow in the sediment of riverbeds have not been very thoroughly studied in the past. During periods of #drought they could become airborne and infect humans and animals.

"When sediments are exposed to air, these fungi may begin to produce many spores that disperse in search of a more suitable environment, and it is during this dispersion that they can interact with humans and animals," study author Josepa Gené, a researcher at the Universitat Rovira i Virgili in Spain, said in a statement.

"The infections tend to affect only the most vulnerable population and are not transmitted between humans," Gené said. "Rather, they are the result of some form of injury, among other routes of inoculation."

These fungi may also be able to infect animals and humans that swim in the rivers where they are living.

"Other fungi are opportunistic pathogens of mammals, cold-blooded animals, and other creatures, which can cause mild and serious infections, not only in animals that live in the aquatic environment but also to those that they pass through it, like us when we have a swim in a river," Gené explained.

The new species of fungus fall into the category of ascomycetes, which include #yeasts like Saccharomyces cerevisiae (used in baking and brewing), filamentous fungi like #Penicillium (which produces the antibiotic penicillin), and various plant pathogens such as the powdery #mildews and #ergot fungi.

"Among their unique characteristics, fungi feed on organic matter by decomposing it, rather than ingesting it like animals do, or absorbing nutrients through roots, as plants do," Rodney Rohde, a Regents' professor of clinical laboratory science at Texas State University, told Newsweek. "Unlike bacteria, which have simple prokaryotic cells, or cells without a true nucleus, fungi have complex eukaryotic cells, which do have a nucleus surrounded by a membrane-like animals and plants.

"In the multi-level taxonomy, or naming system, that biologists use to classify lifeforms, fungi are in their own kingdom under the domain of Eukarya. Since fungi are eukaryotic-like human cells, antibiotics are not effective and we must rely on anti-fungal medications."

The research and a further investigation could help biologists understand the potential threat posed by these fungi, and identify more like them in different environments.

"These findings allow us not only to complete our understanding of the evolution of fungi but also to determine if some of these microorganisms may be a threat to our health," Gené said. "The research has just begun but the more information we accumulate in this regard, the more able we will be to determine, for example, if there is greater potential risk in a particular area and if access to some areas needs to be controlled."

The researchers plan to investigate the fungi in the lab to see how they operate and grow at human body temperature, thus determining their pathogenic potential. This will show how likely it is that the fungus could infect people during periods of drought.

"The thing is that we have a greater understanding of them now, so we can consider establishing environmental control measures. But, before we do, there is still a lot of work to be done," Gené said.

msn.com/en-us/news/technology/

www.msn.comMSN

#Glyphosate, pathways to modern diseases II: #Celiac #sprue and #GlutenIntolerance

2013 December
Anthony Samsel and Stephanie Seneff

"Evidence of disruption of #GutBacteria by glyphosate is available for poultry (Shehata et al., 2013), cattle (Krüger et al., 2013), and swine (Carman et al., 2013). Glyphosate disrupts the balance of gut bacteria in poultry (Shehata et al., 2013), increasing the ratio of #pathogenic #bacteria to other commensal microbes. #Salmonella and #Clostridium are highly resistant to glyphosate, whereas Enterococcus, Bifidobacteria, and Lactobacillus are especially susceptible. Glyphosate was proposed as a possible factor in the increased risk to Clostridium botulinum infection in cattle in Germany over the past ten to fifteen years (Krüger et al., 2013b). Pigs fed GMO corn and soy developed widespread intestinal #inflammation that may have been due in part to glyphosate exposure (Carman et al., 2013).

"Glyphosate Effect: #Desulfovibrio overgrowth
Dysfunction: hydrogen sulfide gas
Result: inflammation"

Full article:
ncbi.nlm.nih.gov/pmc/articles/

PubMed Central (PMC)Glyphosate, pathways to modern diseases II: Celiac sprue and gluten intoleranceCeliac disease, and, more generally, gluten intolerance, is a growing problem worldwide, but especially in North America and Europe, where an estimated 5% of the population now suffers from it. Symptoms include nausea, diarrhea, skin rashes, macrocytic ...

#Cancer is triggered by changes in #cells that lead to the proliferation of #pathogenic #tumor cells. In order to find the most effective combination and dosage of #drugs, it is advantageous if physicians can see inside the body, so to speak, and determine what effect the drugs will have on individual cells.
#Medical #Biology #ArtificialIntelligence #sflorg
sflorg.com/2023/10/med10042301

www.sflorg.comPredictions of the effect of drugs on individual cells are now possibleCancer is triggered by changes in cells that lead to the proliferation of pathogenic tumor cells