Shakedown Social

Radical AnthropologyA fascinating preprint investigating the 'mechanical morphogenesis' -- the complex shapes generated by growth and expansion of <a href="https://c.im/tags/brains" class="mention hashtag" rel="nofollow noopener" target="_blank">#brains</a>. This compares 70 species of New World vs Old World <a href="https://c.im/tags/monkeys" class="mention hashtag" rel="nofollow noopener" target="_blank">#monkeys</a>. As Katja Heuer <a href="https://mstdn.social/@k4tj4" class="u-url mention" rel="nofollow noopener" target="_blank">@k4tj4</a> asks: 'To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape?' Complex shape figures as a 3rd major factor along with genetic inheritance and experience.<a href="https://c.im/tags/primates" class="mention hashtag" rel="nofollow noopener" target="_blank">#primates</a> <a href="https://c.im/tags/evolution" class="mention hashtag" rel="nofollow noopener" target="_blank">#evolution</a> <a href="https://c.im/tags/development" class="mention hashtag" rel="nofollow noopener" target="_blank">#development</a> <a href="https://c.im/tags/phylogeny" class="mention hashtag" rel="nofollow noopener" target="_blank">#phylogeny</a> <a href="https://c.im/tags/morphogenesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#morphogenesis</a><a href="https://www.biorxiv.org/content/10.1101/2025.07.17.665410v1" rel="nofollow noopener" translate="no" target="_blank">https://www.biorxiv.org/content/10.1101/2025.07.17.665410v1</a>

PLOS BiologyHow does transcriptional patterning regulate <a href="https://fediscience.org/tags/SalivaryGland" class="mention hashtag" rel="nofollow noopener" target="_blank">#SalivaryGland</a> <a href="https://fediscience.org/tags/morphogenesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#morphogenesis</a>? Annabel May & <a href="https://bird.makeup/users/katjaroeper" class="u-url mention" rel="nofollow noopener" target="_blank">@katjaroeper</a> use <a href="https://fediscience.org/tags/scRNAseq" class="mention hashtag" rel="nofollow noopener" target="_blank">#scRNAseq</a> of early morphogenesis of the <a href="https://fediscience.org/tags/Drosophila" class="mention hashtag" rel="nofollow noopener" target="_blank">#Drosophila</a> salivary gland placode to reveal regulation by induction & exclusion of regulatory factors <a href="https://fediscience.org/@PLOSBiology" class="u-url mention" rel="nofollow noopener" target="_blank">@PLOSBiology</a> <a href="https://plos.io/4cUw827" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/4cUw827</a>

Emilia Jarochowska 🇺🇦🌱Sir, ma'am, do you have a minute to talk about <a href="https://circumstances.run/tags/evolution" class="mention hashtag" rel="nofollow noopener" target="_blank">#evolution</a>? In these gloomy days, teaching <a href="https://circumstances.run/tags/evolution" class="mention hashtag" rel="nofollow noopener" target="_blank">#evolution</a> is the safe harbour. Tomorrow the lecture is online, because I (and many students) are going to a strike in <a href="https://circumstances.run/tags/Utrecht" class="mention hashtag" rel="nofollow noopener" target="_blank">#Utrecht</a> against budget cuts to higher education 🟥 , but I hope they will still enjoy these absolute classics:Niklas, Karl J. "Evolutionary walks through a land plant morphospace." Journal of Experimental Botany 50.330 (1999): 39-52.I still remember being awe-struck by the work of Karl Niklas on plant <a href="https://circumstances.run/tags/biophysics" class="mention hashtag" rel="nofollow noopener" target="_blank">#biophysics</a> and <a href="https://circumstances.run/tags/morphogenesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#morphogenesis</a> when I was a 1st year student at the University of Warsaw. This was truly a portal to a world where everything in nature could be explained and had an underlying principle.Budd, Graham E. "Morphospace." Current Biology 31.19 (2021): R1181-R1185.While I am learning my part in French to explain <a href="https://circumstances.run/tags/simulations" class="mention hashtag" rel="nofollow noopener" target="_blank">#simulations</a> of <a href="https://circumstances.run/tags/evolution" class="mention hashtag" rel="nofollow noopener" target="_blank">#evolution</a> in Brussels for a Science is Wonderful show by <a href="https://respublicae.eu/@ERC_Research" class="u-url mention" rel="nofollow noopener" target="_blank">@ERC_Research</a> later this week.

Jocelyn Etienne – researchOur article on the <a href="https://mathstodon.xyz/tags/mechanics" class="mention hashtag" rel="nofollow noopener" target="_blank">#mechanics</a> of "active" entropic biopolymer networks [possibly including <a href="https://mathstodon.xyz/tags/actomyosin" class="mention hashtag" rel="nofollow noopener" target="_blank">#actomyosin</a>, this is debated experimentally] is now published in J Elas.Compared to enthalpic models, we're able to go right from the <a href="https://mathstodon.xyz/tags/thermodynamics" class="mention hashtag" rel="nofollow noopener" target="_blank">#thermodynamics</a> of an unbiased <a href="https://mathstodon.xyz/tags/molecularMotor" class="mention hashtag" rel="nofollow noopener" target="_blank">#molecularMotor</a> activity (in the spirit of the model by <a href="https://mathstodon.xyz/tags/JacquesProst" class="mention hashtag" rel="nofollow noopener" target="_blank">#JacquesProst</a> for <a href="https://mathstodon.xyz/tags/myosin" class="mention hashtag" rel="nofollow noopener" target="_blank">#myosin</a>) at the molecular scale to a network-scale model in a closed form.And we derive a method for solving quite easily the (usually tough) <a href="https://mathstodon.xyz/tags/viscoelastic" class="mention hashtag" rel="nofollow noopener" target="_blank">#viscoelastic</a> <a href="https://mathstodon.xyz/tags/liquid" class="mention hashtag" rel="nofollow noopener" target="_blank">#liquid</a> model that we obtain, using <a href="https://mathstodon.xyz/tags/deformationGradientDecomposition" class="mention hashtag" rel="nofollow noopener" target="_blank">#deformationGradientDecomposition</a>.<a href="https://doi.org/10.1007/s10659-024-10102-8" rel="nofollow noopener" translate="no" target="_blank">https://doi.org/10.1007/s10659-024-10102-8</a> (I share a paywall-free link to my followers below, but it's also on arXiv: <a href="https://arxiv.org/abs/2405.07287" rel="nofollow noopener" translate="no" target="_blank">https://arxiv.org/abs/2405.07287</a> and on my webpage <a href="https://liphy-annuaire.univ-grenoble-alpes.fr/pages_personnelles/jocelyn_etienne/papers.html#Jallon+Etienne.2025.1" rel="nofollow noopener" translate="no" target="_blank">https://liphy-annuaire.univ-grenoble-alpes.fr/pages_personnelles/jocelyn_etienne/papers.html#Jallon+Etienne.2025.1</a>)<a href="https://mathstodon.xyz/tags/cytoskeleton" class="mention hashtag" rel="nofollow noopener" target="_blank">#cytoskeleton</a> <a href="https://mathstodon.xyz/tags/cell" class="mention hashtag" rel="nofollow noopener" target="_blank">#cell</a> <a href="https://mathstodon.xyz/tags/tissue" class="mention hashtag" rel="nofollow noopener" target="_blank">#tissue</a> <a href="https://mathstodon.xyz/tags/morphogenesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#morphogenesis</a> <a href="https://mathstodon.xyz/tags/activeMatter" class="mention hashtag" rel="nofollow noopener" target="_blank">#activeMatter</a> <a href="https://mathstodon.xyz/tags/livingMatter" class="mention hashtag" rel="nofollow noopener" target="_blank">#livingMatter</a>

PLOS BiologyHow is cell basal geometry is regulated during epithelial <a href="https://fediscience.org/tags/morphogenesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#morphogenesis</a>? @PichaudLab &co show that a pathway involving <a href="https://fediscience.org/tags/laminin" class="mention hashtag" rel="nofollow noopener" target="_blank">#laminin</a> & <a href="https://fediscience.org/tags/integrin" class="mention hashtag" rel="nofollow noopener" target="_blank">#integrin</a> adhesion coordinates remodelling of <a href="https://fediscience.org/tags/EpithelialCell" class="mention hashtag" rel="nofollow noopener" target="_blank">#EpithelialCell</a> shape by patterning their basement membrane <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#PLOSBiology</a> <a href="https://plos.io/4e457co" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/4e457co</a>

PLOS BiologyThe <a href="https://fediscience.org/tags/notochord" class="mention hashtag" rel="nofollow noopener" target="_blank">#notochord</a> is an essential tubular organ that defines the phylum <a href="https://fediscience.org/tags/Chordata" class="mention hashtag" rel="nofollow noopener" target="_blank">#Chordata</a>. @ZonglaiL @daniel_dondorp @mchlab reveal that the <a href="https://fediscience.org/tags/IonChannel" class="mention hashtag" rel="nofollow noopener" target="_blank">#IonChannel</a> Anoctamin 10 orchestrates <a href="https://fediscience.org/tags/morphogenesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#morphogenesis</a> of the notochord in the <a href="https://fediscience.org/tags/urochordate" class="mention hashtag" rel="nofollow noopener" target="_blank">#urochordate</a> <a href="https://fediscience.org/tags/SeaSquirt" class="mention hashtag" rel="nofollow noopener" target="_blank">#SeaSquirt</a> Ciona <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#PLOSBiology</a> <a href="https://plos.io/3SZMpdo" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/3SZMpdo</a>

PLOS BiologyExposure to <a href="https://fediscience.org/tags/ether" class="mention hashtag" rel="nofollow noopener" target="_blank">#ether</a> messes up wing development in <a href="https://fediscience.org/tags/Drosophila" class="mention hashtag" rel="nofollow noopener" target="_blank">#Drosophila</a>. @OrliSnir @ElgartMichael &co reveal the <a href="https://fediscience.org/tags/epigenetic" class="mention hashtag" rel="nofollow noopener" target="_blank">#epigenetic</a> basis of this, showing how environmental disruption of protein integrity can shift epigenetic patterning to shape <a href="https://fediscience.org/tags/morphogenesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#morphogenesis</a> <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#PLOSBiology</a> <a href="https://plos.io/3QZwfj1" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/3QZwfj1</a>

Karsten Schmidt"The limits of my language mean the limits of my world" — WittgensteinI keep on thinking (again!) about the importance & potential of dedicated programming languages in (not just my own) generative art/design processes and want to make time to write more about it.Example: Creating a custom DSL to describe recursive spatial tree transformations (here only 8 operators) to literally grow complex objects from a _single_ seed shape/box. These objects and their growth visualizations are a few of my fave examples from this 2013/14 research (a project to revisit):<a href="https://thi.ng/morphogen" rel="nofollow noopener" translate="no" target="_blank">https://thi.ng/morphogen</a>The animations are simply visualizing the resulting object of the partially transformed operator trees by artificially limiting recursion depth (increasing it over time)...Ps. The 3.5m tall and 2.4m diameter 3D printed chandelier shown in the last image was generated with the same language & related thi.ng toolchain...<a href="https://mastodon.thi.ng/tags/GenerativeDesign" class="mention hashtag" rel="nofollow noopener" target="_blank">#GenerativeDesign</a> <a href="https://mastodon.thi.ng/tags/Language" class="mention hashtag" rel="nofollow noopener" target="_blank">#Language</a> <a href="https://mastodon.thi.ng/tags/DSL" class="mention hashtag" rel="nofollow noopener" target="_blank">#DSL</a> <a href="https://mastodon.thi.ng/tags/Recursion" class="mention hashtag" rel="nofollow noopener" target="_blank">#Recursion</a> <a href="https://mastodon.thi.ng/tags/Geometry" class="mention hashtag" rel="nofollow noopener" target="_blank">#Geometry</a> <a href="https://mastodon.thi.ng/tags/Biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#Biology</a> <a href="https://mastodon.thi.ng/tags/Morphogenesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#Morphogenesis</a>

Bruno C. VellutiniHi <a href="https://mastodon.social/tags/ScienceMastodon" class="mention hashtag" rel="nofollow noopener" target="_blank">#ScienceMastodon</a>, time for an <a href="https://mastodon.social/tags/introduction" class="mention hashtag" rel="nofollow noopener" target="_blank">#introduction</a>!I'm an <a href="https://mastodon.social/tags/EvoDevo" class="mention hashtag" rel="nofollow noopener" target="_blank">#EvoDevo</a> biologist interested in how tissue <a href="https://mastodon.social/tags/mechanics" class="mention hashtag" rel="nofollow noopener" target="_blank">#mechanics</a> influences the <a href="https://mastodon.social/tags/evolution" class="mention hashtag" rel="nofollow noopener" target="_blank">#evolution</a> of <a href="https://mastodon.social/tags/morphogenesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#morphogenesis</a>. I study a deep and mysterious epithelial invagination that forms at the head-trunk boundary of <a href="https://mastodon.social/tags/flies" class="mention hashtag" rel="nofollow noopener" target="_blank">#flies</a> during <a href="https://mastodon.social/tags/gastrulation" class="mention hashtag" rel="nofollow noopener" target="_blank">#gastrulation</a>, known as the <a href="https://mastodon.social/tags/CephalicFurrow" class="mention hashtag" rel="nofollow noopener" target="_blank">#CephalicFurrow</a> (see video below!). Currently, based in Germany as a postdoc in the Tomancak Lab at MPI-CBG. Looking forward to meeting you!<a href="https://mastodon.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#DevBio</a> <a href="https://mastodon.social/tags/mechanobiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#mechanobiology</a> <a href="https://mastodon.social/tags/microscopy" class="mention hashtag" rel="nofollow noopener" target="_blank">#microscopy</a> <a href="https://mastodon.social/tags/lightsheet" class="mention hashtag" rel="nofollow noopener" target="_blank">#lightsheet</a> <a href="https://mastodon.social/tags/embryos" class="mention hashtag" rel="nofollow noopener" target="_blank">#embryos</a>

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