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#microrna

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Flipboard Science Desk<p>New Nobel laureate Victor Ambros describes the scientific process of discovering MicroRNA.</p><p>The Conversation Weekly podcast caught up with Ambros from his lab at the UMass Chan Medical School to learn more about the Nobel-winning research and what comes next. Here are edited excerpts from <span class="h-card" translate="no"><a href="https://newsie.social/@TheConversationUS" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>TheConversationUS</span></a></span>: <a href="https://flip.it/oB-EhP" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">flip.it/oB-EhP</span><span class="invisible"></span></a></p><p><a href="https://flipboard.social/tags/Nobel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Nobel</span></a> <a href="https://flipboard.social/tags/MicroRNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MicroRNA</span></a> <a href="https://flipboard.social/tags/Science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Science</span></a> <a href="https://flipboard.social/tags/DNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DNA</span></a> <a href="https://flipboard.social/tags/Biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Biology</span></a></p>
Flipboard<p>Two scientists from Massachusetts won this year’s Nobel Prize in physiology or medicine. Victor Ambros and Gary Ruvkun were honored for their discovery of microRNA — research that is having profound effects on our understanding of how cells and organisms work. <span class="h-card" translate="no"><a href="https://mastodon.social/@gbhnews" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>gbhnews</span></a></span> wrote about the scientists’ responses to their prize. “The surprises are what keep you young in science,” Ruvkun said. “And so I am constantly surprised. And my ignorance is bliss.”</p><p><a href="https://www.wgbh.org/news/local/2024-10-07/pay-attention-to-revolutions-mass-scientists-win-nobel-prize-in-medicine-for-discovery-of-microrna" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">wgbh.org/news/local/2024-10-07</span><span class="invisible">/pay-attention-to-revolutions-mass-scientists-win-nobel-prize-in-medicine-for-discovery-of-microrna</span></a></p><p><a href="https://flipboard.social/tags/Science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Science</span></a> <a href="https://flipboard.social/tags/NobelPrizeinMedicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>NobelPrizeinMedicine</span></a> <a href="https://flipboard.social/tags/microRNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>microRNA</span></a> <a href="https://flipboard.social/tags/Boston" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Boston</span></a> <a href="https://flipboard.social/tags/Newstodon" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Newstodon</span></a> <a href="https://flipboard.social/tags/NewstodonFriday" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>NewstodonFriday</span></a> <a href="https://flipboard.social/tags/FollowFriday" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>FollowFriday</span></a></p>
The Japan Times<p>Funding science that might not lead anywhere is often how we end up with breakthroughs. <a href="https://www.japantimes.co.jp/commentary/2024/10/09/world/nobel-prize-medicine-microrna/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">japantimes.co.jp/commentary/20</span><span class="invisible">24/10/09/world/nobel-prize-medicine-microrna/</span></a> <a href="https://mastodon.social/tags/commentary" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>commentary</span></a> <a href="https://mastodon.social/tags/worldnews" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>worldnews</span></a> <a href="https://mastodon.social/tags/microrna" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>microrna</span></a> <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>science</span></a> <a href="https://mastodon.social/tags/health" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>health</span></a> <a href="https://mastodon.social/tags/medicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medicine</span></a> <a href="https://mastodon.social/tags/nobelprize" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>nobelprize</span></a></p>
Chuck Darwin<p>Two American scientists -- Victor Ambros and Gary Ruvkun -- won the <a href="https://c.im/tags/Nobel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Nobel</span></a> <a href="https://c.im/tags/Prize" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Prize</span></a> in physiology or medicine on Monday for their discovery of <a href="https://c.im/tags/microRNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>microRNA</span></a>, 🔸tiny bits of genetic material that serve as on and off switches inside cells 🔸that help control what the cells do and when they do it.<br>According to a panel that awarded the prize, the work is “proving to be fundamentally important for how organisms develop and function” <br>Ambros and Ruvkun were initially interested in genes that control the timing of different genetic developments, ensuring that cell types develop at the right time.<br>Their discovery ultimately “revealed a new dimension to gene regulation, essential for all complex life forms<br>If scientists can better understand how microDNA works and how to manipulate it, it could one day lead to powerful treatments for diseases like cancer.<br><a href="https://apnews.com/article/nobel-medicine-dc84622d7a15317bc83e873d3f9a2dbf" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">apnews.com/article/nobel-medic</span><span class="invisible">ine-dc84622d7a15317bc83e873d3f9a2dbf</span></a></p>
Photo Ewen 📷<p>MicroRNA the Nobel Prize for Medicine.</p><p>In 1993 when this discovery was first hatching, I was 23 years old and learning to appreciate the difference between what we know about the world, and what we don't. The idea that tiny fragments of RNA might be regulating gene expression is pretty wild stuff. But that's the point of science... Learning new things about the natural world is a magnificent journey to be on. </p><p><a href="https://photog.social/tags/MicroRNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MicroRNA</span></a> <a href="https://photog.social/tags/Science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Science</span></a> <a href="https://photog.social/tags/NobelPrize" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>NobelPrize</span></a></p>
Preston MacDougall<p>The 2024 <a href="https://mstdn.science/tags/NobelPrize" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>NobelPrize</span></a> in Physiology/#Medicine has been awarded to Victor Ambros and Gary Ruvkun in <a href="https://mstdn.science/tags/Massachusetts" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Massachusetts</span></a> , both conducting research on <a href="https://mstdn.science/tags/GeneRegulation" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>GeneRegulation</span></a> by <a href="https://mstdn.science/tags/microRNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>microRNA</span></a> in 🪱. <a href="https://mstdn.science/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>science</span></a> <a href="https://mstdn.science/tags/genetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>genetics</span></a> </p><p><a href="https://www.nobelprize.org/prizes/medicine/2024/press-release/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nobelprize.org/prizes/medicine</span><span class="invisible">/2024/press-release/</span></a></p>
Auscandoc<p>Citations of <a href="https://med-mastodon.com/tags/microRNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>microRNA</span></a> Biomarker Articles That Were Retracted: A Systematic Review | Medical Journals and Publishing | JAMA Network Open | JAMA Network <a href="https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2816597" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jamanetwork.com/journals/jaman</span><span class="invisible">etworkopen/fullarticle/2816597</span></a> <a href="https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2816597?utm_source=twitter&amp;utm_campaign=content-shareicons&amp;utm_content=article_engagement&amp;utm_medium=social&amp;utm_term=032224" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jamanetwork.com/journals/jaman</span><span class="invisible">etworkopen/fullarticle/2816597?utm_source=twitter&amp;utm_campaign=content-shareicons&amp;utm_content=article_engagement&amp;utm_medium=social&amp;utm_term=032224</span></a> “In this study, <a href="https://med-mastodon.com/tags/retraction" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>retraction</span></a> was not associated with a reduction in <a href="https://med-mastodon.com/tags/citations" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>citations</span></a> of retracted articles, but articles that cited retracted publications had higher odds of later retraction. These findings suggest that journals may need to implement mechanisms for detection of postretraction citations.”</p>
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