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#metastasis

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PLOS Biology<p>The K+ channel KCNK1 is differentially expressed in many <a href="https://fediscience.org/tags/tumors" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>tumors</span></a>, but why? Study shows that KCNK1 overexpression in <a href="https://fediscience.org/tags/BreastCancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>BreastCancer</span></a> promotes proliferation, invasion &amp; <a href="https://fediscience.org/tags/metastasis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>metastasis</span></a> by increasing <a href="https://fediscience.org/tags/glycolysis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>glycolysis</span></a> &amp; activating <a href="https://fediscience.org/tags/LactateDehydrogenase" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LactateDehydrogenase</span></a>. <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PLOSBiology</span></a> <a href="https://plos.io/3VTNdCr" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3VTNdCr</span><span class="invisible"></span></a></p>
Matt Willemsen<p>AI traces mysterious metastatic cancers to their source<br><a href="https://www.nature.com/articles/d41586-024-01110-8" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/d41586-024</span><span class="invisible">-01110-8</span></a> <a href="https://mastodon.social/tags/AI" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>AI</span></a> <a href="https://mastodon.social/tags/cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cancer</span></a> <a href="https://mastodon.social/tags/metastasis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>metastasis</span></a> <a href="https://mastodon.social/tags/origins" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>origins</span></a> <a href="https://mastodon.social/tags/PrimaryTumour" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PrimaryTumour</span></a></p>
PLOS Biology<p>How important is epithelial-to-mesenchymal transition (EMT) for <a href="https://fediscience.org/tags/cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cancer</span></a> metastasis? </p><p>In this <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PLOSBiology</span></a> Unsolved Mystery, the authors look at ongoing research surrounding <a href="https://fediscience.org/tags/EMT" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>EMT</span></a> in <a href="https://fediscience.org/tags/metastasis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>metastasis</span></a> and the potential it could hold for developing new therapeutic avenues.</p><p><a href="https://plos.io/48aFAdC" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="">plos.io/48aFAdC</span><span class="invisible"></span></a></p>
PLOS Biology<p>Non-canonical role of the E3 <a href="https://fediscience.org/tags/ubiquitin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ubiquitin</span></a> ligase FBXO3 in PI3K-induced <a href="https://fediscience.org/tags/BreastCancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>BreastCancer</span></a> <a href="https://fediscience.org/tags/metastasis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>metastasis</span></a>: FBXO3 binds &amp; protects USP4 from DNPEP-mediated degradation, resulting in Twist1 protein stabilization &amp; increased <a href="https://fediscience.org/tags/tumor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>tumor</span></a> metastasis <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PLOSBiology</span></a> <a href="https://plos.io/3twkOan" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3twkOan</span><span class="invisible"></span></a></p>
Scientific Frontline<p>The most lethal feature of any <a href="https://mastodon.social/tags/cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cancer</span></a> is <a href="https://mastodon.social/tags/metastasis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>metastasis</span></a> the spread of cancer cells throughout the body. New research led by Penn State reveals for the first time the mechanics behind how <a href="https://mastodon.social/tags/breast" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>breast</span></a> cancer cells may invade healthy tissues. <br><a href="https://mastodon.social/tags/Biology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Biology</span></a> <a href="https://mastodon.social/tags/Chemistry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Chemistry</span></a> <a href="https://mastodon.social/tags/Engineering" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Engineering</span></a> <a href="https://mastodon.social/tags/Medical" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Medical</span></a> <a href="https://mastodon.social/tags/Pharmaceutical" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Pharmaceutical</span></a> <a href="https://mastodon.social/tags/sflorg" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>sflorg</span></a><br><a href="https://www.sflorg.com/2023/10/bio10282301.html" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">sflorg.com/2023/10/bio10282301</span><span class="invisible">.html</span></a></p>
Scientific Frontline<p>A new mouse study indicates that it is possible to reduce the risk of <a href="https://mastodon.social/tags/metastasis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>metastasis</span></a> formation from <a href="https://mastodon.social/tags/lung" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>lung</span></a> <a href="https://mastodon.social/tags/cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cancer</span></a> and improve the effectiveness of the medication <a href="https://mastodon.social/tags/Cisplatin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Cisplatin</span></a>, often administered to lung cancer patients. The agent is the substance propionate, which is currently being tested as a treatment for obesity and diabetes.<br><a href="https://mastodon.social/tags/Biology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Biology</span></a> <a href="https://mastodon.social/tags/Medical" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Medical</span></a> <a href="https://mastodon.social/tags/Pharmaceutical" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Pharmaceutical</span></a> <a href="https://mastodon.social/tags/sflorg" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>sflorg</span></a><br><a href="https://www.sflorg.com/2023/10/med10112301.html" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">sflorg.com/2023/10/med10112301</span><span class="invisible">.html</span></a></p>
Janice Selbie<p>GO, SCIENCE! <a href="https://mas.to/tags/cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cancer</span></a> <a href="https://mas.to/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>science</span></a> <a href="https://mas.to/tags/medicine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>medicine</span></a> <a href="https://mas.to/tags/metastasis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>metastasis</span></a> <a href="https://mas.to/tags/mystery" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>mystery</span></a> <br>Scientists solve the mystery of cancer metastasis <a href="https://knowridge.com/2023/09/scientists-solve-the-mystery-of-cancer-metastasis/" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">knowridge.com/2023/09/scientis</span><span class="invisible">ts-solve-the-mystery-of-cancer-metastasis/</span></a></p>
PLOS Biology<p>A novel TOX3-WDR5-H3K4me3/ABCG2 signaling axis is upregulated in <a href="https://fediscience.org/tags/ColorectalCancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ColorectalCancer</span></a> (CRC) <a href="https://fediscience.org/tags/StemCells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>StemCells</span></a>; these proteins may act as biomarkers for predicting CRC survival, and targets for countering drug tolerance, recurrence &amp; <a href="https://fediscience.org/tags/metastasis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>metastasis</span></a> <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PLOSBiology</span></a> <a href="https://plos.io/3ZliKgx" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3ZliKgx</span><span class="invisible"></span></a></p>
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