Shakedown Social

Psychedelic Institute<a href="https://pubmed.ncbi.nlm.nih.gov/40468911/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250605063119&v=2.18.0.post9+e462414" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40468911/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250605063119&v=2.18.0.post9+e462414</a> Six weeks open-label oral ketamine for patients with treatment-resistant depression, post-traumatic stress disorder, or obsessive-compulsive disorder (Beaglehole, 2025) <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a>

Psychedelic InstituteWhat’s Perfusion Got to Do With It? <a href="https://flip.it/Fnj7sG" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://flip.it/Fnj7sG</a> <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a> <a href="https://mastodon.social/tags/brains" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#brains</a> <a href="https://mastodon.social/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a>

Psychedelic Institute<a href="https://genomicpress.kglmeridian.com/view/journals/genpsych/aop/article-10.61373-gp025c.0041/article-10.61373-gp025c.0041.xml" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://genomicpress.kglmeridian.com/view/journals/genpsych/aop/article-10.61373-gp025c.0041/article-10.61373-gp025c.0041.xml</a> The salience network is functionally twice as large in depression: The first depression biomarker? (Palacek, et al, 2025) <a href="https://mastodon.social/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelictherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelictherapy</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/anxiety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#anxiety</a> <a href="https://mastodon.social/tags/ptsd" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ptsd</a> <a href="https://mastodon.social/tags/trauma" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#trauma</a> <a href="https://mastodon.social/tags/anorexia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#anorexia</a> Big Salience Network Energy.

Psychedelic InstituteEffects of ketamine on individual symptoms and symptom networks of depression in a randomised controlled trial of ketamine for treatment-resistant depression (Hossein, et al, 2025) <a href="https://pubmed.ncbi.nlm.nih.gov/40355133/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40355133/</a> <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/ketamineassistedtherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamineassistedtherapy</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a>

Psychedelic InstituteEnhanced ERK activity extends ketamine's antidepressant effects by augmenting synaptic plasticity (Ma, et al, 2025) <a href="https://pubmed.ncbi.nlm.nih.gov/40339008/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40339008/</a> <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/ketamineassistedpsychotherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamineassistedpsychotherapy</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/Psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Psychedelics</a> <a href="https://mastodon.social/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a> <a href="https://mastodon.social/tags/psychedelicresearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicresearch</a>

Psychedelic InstituteBreaking through anhedonia: How ketamine reignites the drive for rewards (McClung, 2025) <a href="https://pubmed.ncbi.nlm.nih.gov/40339564/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40339564/</a> <a href="https://mastodon.social/tags/anhedonia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#anhedonia</a> <a href="https://mastodon.social/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/ketamineassistedtherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamineassistedtherapy</a> <a href="https://mastodon.social/tags/ketamineassistedpsychotherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamineassistedpsychotherapy</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a>

Psychedelic InstituteMapping the Use of Ketamine in Treatment-Resistant Depression and Other Psychiatric Disorders: A Scoping Review of Practice Patterns, Efficacy, and Patient Demographic Trends (Aslam, et al, 2025) <a href="https://pubmed.ncbi.nlm.nih.gov/40338681/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40338681/</a> <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/ketamineassistedtherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamineassistedtherapy</a> <a href="https://mastodon.social/tags/ketamineassistedpsychotherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamineassistedpsychotherapy</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelicresearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicresearch</a>

Psychedelic Institute<a href="https://pubmed.ncbi.nlm.nih.gov/40336446/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40336446/</a> [Interventional psychiatric procedures and novel substances for the treatment of affective disorders: An overview and outlook (Bacht, et al, 2025) <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/psychotherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychotherapy</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/ketamineassistedpsychotherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamineassistedpsychotherapy</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelictherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelictherapy</a> <a href="https://mastodon.social/tags/psychedelicassistedpsychotherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicassistedpsychotherapy</a> <a href="https://mastodon.social/tags/psychedelicresearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicresearch</a> <a href="https://mastodon.social/tags/ketamineassistedtherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamineassistedtherapy</a>

Psychedelic InstituteKetamine evokes acute behavioral effects via μ-opioid receptor expressing neurons of the central amygdala (Pomrenze, et al, 2025) <a href="https://pubmed.ncbi.nlm.nih.gov/40334963/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40334963/</a> The CeA and MORs might be critical in triggering the cascade that leads to the broader network plasticity revealed by the recent mesoscale analysis brain network study <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/ketaamineassistedpsychotherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaamineassistedpsychotherapy</a>

Psychedelic InstituteSpotlight: Ketamine’s Rapid Antidepressant Effects Mapped Brain-Wide + μ-opioid receptor? <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelicresearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicresearch</a> <a href="https://mastodon.social/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a> <a href="https://mastodon.social/tags/ketamineassistedpsychotherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamineassistedpsychotherapy</a> <a href="https://psychedelicmentalhealth.net/spotlight-ketamines-rapid-antidepressant-effects-mapped-brain-wide/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://psychedelicmentalhealth.net/spotlight-ketamines-rapid-antidepressant-effects-mapped-brain-wide/</a>

Psychedelic Institute<a href="https://pubmed.ncbi.nlm.nih.gov/40328099/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250507002646&v=2.18.0.post9+e462414" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40328099/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250507002646&v=2.18.0.post9+e462414</a> Can ketamine and other glutamate receptor modulators be considered entactogens? (Hu, et al, 2025) <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/entactogen" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#entactogen</a> <a href="https://mastodon.social/tags/glutamate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#glutamate</a>

Psychedelic Institute<a href="https://psychedelicmentalhealth.net/psychedelics-in-palliative-care-glass-oxford-university-press/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://psychedelicmentalhealth.net/psychedelics-in-palliative-care-glass-oxford-university-press/</a> Pre-order: "Psychedelics in Palliative Care", Marcia Glass, Ed., Oxford University Press with contributions by Psychedelic Institute fellows, Michael DeMarco, PhD and Thaís Salles Araujo, MD on <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a>, <a href="https://mastodon.social/tags/psilocybin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psilocybin</a> mushrooms in palliative care -- I'm so proud to have contributed to this, and dedicate it in memory of my dog Fen <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/palliativecare" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#palliativecare</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/psychedelictherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelictherapy</a> <a href="https://mastodon.social/tags/ketamina" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamina</a>

Psychedelic InstituteRole of ketamine in the treatment of substance use disorders: A systematic review (Jannsen-Aguilar, et al, 2025) <a href="https://pubmed.ncbi.nlm.nih.gov/40320049/#ketamine" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40320049/#ketamine</a> <a href="https://mastodon.social/tags/addiction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#addiction</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/ketamineassistedpsychotherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamineassistedpsychotherapy</a> <a href="https://mastodon.social/tags/substanceusedisorder" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#substanceusedisorder</a> <a href="https://mastodon.social/tags/alcoholusedisorder" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#alcoholusedisorder</a> <a href="https://mastodon.social/tags/recovery" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#recovery</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/ketamineassistedpsychotherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamineassistedpsychotherapy</a>

Psychedelic InstituteQualitative analysis of a patient's experience of ketamine-assisted psychotherapy for substance use disorder: Empirical synergies with twelve-step programs <a href="https://www.sciencedirect.com/science/article/pii/S2773021225000161" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.sciencedirect.com/science/article/pii/S2773021225000161</a> <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/ketamineassistedpsychotherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamineassistedpsychotherapy</a> <a href="https://mastodon.social/tags/ketamineassistedtherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamineassistedtherapy</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelicassistedtherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicassistedtherapy</a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a> <a href="https://mastodon.social/tags/recovery" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#recovery</a> <a href="https://mastodon.social/tags/12step" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#12step</a> <a href="https://mastodon.social/tags/aa" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#aa</a> <a href="https://mastodon.social/tags/alcoholicsanonymous" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#alcoholicsanonymous</a> <a href="https://mastodon.social/tags/substanceusedisorder" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#substanceusedisorder</a> <a href="https://mastodon.social/tags/cognitivebehavioraltherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cognitivebehavioraltherapy</a>

Psychedelic Institute<a href="https://psychedelicmentalhealth.net/spotlight-ketamines-rapid-antidepressant-effects-mapped-brain-wide/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://psychedelicmentalhealth.net/spotlight-ketamines-rapid-antidepressant-effects-mapped-brain-wide/</a> Spotlight: Ketamine’s Rapid Antidepressant Effects Mapped Brain-Wide "The deployment of mesoscale brain-wide fluctuation analysis unveils the complex, multiregional neural orchestration underlying ketamine’s rapid antidepressant effects, a blueprint for future therapeutic innovation... insights gained from this research hold transformative promise..." <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelicresearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicresearch</a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a> <a href="https://mastodon.social/tags/psychiatry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychiatry</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a>

Psychedelic InstituteKetamine’s Rapid Antidepressant Effects Mapped Brain-Wide - SCIENMAG <a href="https://apple.news/AUoWZT7pvRl-hZuRBVO6HNg" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://apple.news/AUoWZT7pvRl-hZuRBVO6HNg</a> <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a> <a href="https://mastodon.social/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelicresearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicresearch</a>

Psychedelic Institute<a href="https://pubmed.ncbi.nlm.nih.gov/40311741/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250502003505&v=2.18.0.post9+e462414" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40311741/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250502003505&v=2.18.0.post9+e462414</a> Beyond surgery: Repurposing anesthetics for treatment of central nervous system disorders (Mielko, et al, 2025) <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a>

Psychedelic Institute<a href="https://pubmed.ncbi.nlm.nih.gov/40311814/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250502003505&v=2.18.0.post9+e462414" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40311814/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250502003505&v=2.18.0.post9+e462414</a> Glutamate plus glutamine to GABA ratio as a predictor of ketamine response in treatment-resistant depression: A double-blind, randomized, open-label extension study (Ohtani, et al 2025) <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/glutamate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#glutamate</a> <a href="https://mastodon.social/tags/brains" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#brains</a> <a href="https://mastodon.social/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a>

Psychedelic Institute<a href="https://pubmed.ncbi.nlm.nih.gov/40313650/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250502062629&v=2.18.0.post9+e462414" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40313650/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250502062629&v=2.18.0.post9+e462414</a> Intravenous Ketamine Treatment for Depression: One-year Retrospective Study from a Tertiary Care Psychiatry Center from India (Yadev, et al, 2025) <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelicresesrch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicresesrch</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/ketaminesafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminesafety</a> <a href="https://mastodon.social/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a>

Psychedelic InstituteOral Ketamine as an Analgesic Therapy: Systematic Review of Randomised Clinical Trials (Umbacia, et al, 2025) <a href="https://pubmed.ncbi.nlm.nih.gov/40306314/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40306314/</a> " Preliminary evidence suggests that oral ketamine may be considered in select patients with refractory chronic neuropathic pain." <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/palliativecare" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#palliativecare</a> <a href="https://mastodon.social/tags/painmanagement" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#painmanagement</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelicresearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicresearch</a>

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