Researchers Discover a New Combination Therapy Effective Against Drug-Sensitive and Resistant Parasites
Drug-resistant babesiosis may respond to a novel combination therapy, researchers say.
The treatment, which involves the antimalarial drug #tafenoquine and the anti-fungal/anti-parasite drug #atovaquone, may also provide immunity against future babesiosis infections.
The findings were published on January 3 in the Journal of Infectious Diseases.
We identified a specific combination of drugs that clears Babesia parasites effectively—including the drug-resistant parasites.
Pratap Vydyam, PhD
#Babesiosis is a tickborne illness caused by Babesia parasites that develop and multiply in red blood cells.
Its symptoms include fevers, chills, sweats, and fatigue, and in severe cases, can be life-threatening.
Incidence of the disease is rapidly rising, particularly in the Northeast.
A 2023 report from the Centers for Disease Control and Prevention (CDC) warns that cases grew by 25% between 2011 and 2019.
Beyond #tick bites, babesiosis can also be spread through contaminated blood transfusions or during pregnancy or delivery if the mother is infected
https://medicine.yale.edu/news-article/babesiosis-researchers-discover-a-new-combination-therapy-effective-against-drug-sensitive-and-resistant-parasites/