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#ModelOrganism

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Dr. John Barentine FRAS<p>"Zebrafish exposed to light pollution at night showed signs of anxiety, such as swimming less and staying close to aquarium walls. The next generation of zebrafish also showed anxiety-related behaviors, even without direct exposure to the light, suggesting lasting effects across generations." </p><p><a href="https://earthsky.org/earth/light-pollution-fish-next-generation/" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">earthsky.org/earth/light-pollu</span><span class="invisible">tion-fish-next-generation/</span></a></p><p><a href="https://astrodon.social/tags/ALAN" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ALAN</span></a> <a href="https://astrodon.social/tags/LightPollution" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LightPollution</span></a> <a href="https://astrodon.social/tags/ModelOrganism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ModelOrganism</span></a></p>
Dr. Robert M Flight<p>There was someone, like 10 years ago set up a biotech in California that was focused on making known patient mutations in really simple, highly reproductive model organisms (yeast, fly, worm), and then testing a variety of compounds to see if they resulted in the rescue phenotype.</p><p>I know they concentrated on lipid processing mutations initially.</p><p>I was describing this to someone, and could not remember the name of the person or company.</p><p><a href="https://mastodon.social/tags/genomics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>genomics</span></a> <a href="https://mastodon.social/tags/biotech" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>biotech</span></a> <a href="https://mastodon.social/tags/ModelOrganism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ModelOrganism</span></a></p>
Verena Kohler<p><a href="https://fediscience.org/tags/Introduction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Introduction</span></a>:</p><p>Hello <a href="https://fediscience.org/tags/ScienceMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ScienceMastodon</span></a>.</p><p>My name is Verena Kohler and I am a <a href="https://fediscience.org/tags/FirstGen" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>FirstGen</span></a> <a href="https://fediscience.org/tags/scientist" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>scientist</span></a>, currently working as independent senior <a href="https://fediscience.org/tags/postdoc" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>postdoc</span></a> at <a href="https://fediscience.org/tags/UniGraz" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>UniGraz</span></a> in Austria. </p><p>I am interested, how age influences <a href="https://fediscience.org/tags/proteostasis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>proteostasis</span></a>, the balance between protein production, folding and degradation, and how <a href="https://fediscience.org/tags/ageing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ageing</span></a> affects cellular <a href="https://fediscience.org/tags/communication" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>communication</span></a> routes.<br>For that, I am using my favourite <a href="https://fediscience.org/tags/ModelOrganism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ModelOrganism</span></a>, the baker’s <a href="https://fediscience.org/tags/yeast" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>yeast</span></a>, a lot of <a href="https://fediscience.org/tags/FluorescenceMicroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>FluorescenceMicroscopy</span></a> and <a href="https://fediscience.org/tags/HighThroughput" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>HighThroughput</span></a> screens.</p><p>Let’s talk <a href="https://fediscience.org/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>science</span></a> !</p>