Shakedown Social

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LorraineThe great thing about high profile moron “experts” making blithe uninformed comments such as “Covid doesn’t really damage the immune system” is it angers people who ACTUALLY know & they come at them with <a href="https://zeroes.ca/tags/CovidPapers" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CovidPapers</a> <a href="https://zeroes.ca/tags/Jha" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Jha</a>This will be my continuing🧵on anything related to the destruction of <a href="https://zeroes.ca/tags/tcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#tcells</a> <a href="https://zeroes.ca/tags/bcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bcells</a> <a href="https://zeroes.ca/tags/ImmuneDysregulation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ImmuneDysregulation</a> in an attempt to be organized if only for myself🖤Published January 14, 2022 <a href="https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-021-02228-6" rel="nofollow noopener noreferrer" target="_blank">https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-021-02228-6</a>In truth just skimmed but my grasp on this in January 2024 is something that would have been impossible for me to understand in 2022 while experiencing my <a href="https://zeroes.ca/tags/sarscov2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#sarscov2</a> 2nd infection b/c my level of biology was zero & my lack of understanding led me to believe <a href="https://zeroes.ca/tags/hybridImmunity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#hybridImmunity</a> would give me 2 years at least. Mind you I never took my mask off except w/my MIL🦃🎄2021Philip Dettmer “immune” book along w/the incredibly intelligent🧠🧠🧠here🐘&🐦have been invaluable in at least allowing me to read & generally follow alongBasically this study tells me, stay down for 6 months minimum

LorraineOn a totally unrelated note🙄 <a href="https://www.youtube.com/watch?v=BlQOgs9fzc4" rel="nofollow noopener noreferrer" target="_blank">https://www.youtube.com/watch?v=BlQOgs9fzc4</a>I know :deadbirb: :twitterfire: is bad, but I do love sue @🖤 inkblue01 who has the best info <a href="https://zeroes.ca/tags/tcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#tcells</a> <a href="https://zeroes.ca/tags/bcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bcells</a> <a href="https://zeroes.ca/tags/cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cancer</a>

Alan KotokElectric Pulses Induce Lung Cancer Immune ResponseResults of a clinical trial show a lung cancer therapy using highly focused pulses with electrical energy show signs of immune responses that can treat the patients' tumors.<a href="https://sciencebusiness.technewslit.com/?p=45375" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://sciencebusiness.technewslit.com/?p=45375</a><a href="https://journa.host/tags/News" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#News</a> <a href="https://journa.host/tags/Press" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Press</a> <a href="https://journa.host/tags/Science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Science</a> <a href="https://journa.host/tags/Business" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Business</a> <a href="https://journa.host/tags/Cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Cancer</a> <a href="https://journa.host/tags/LungCancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#LungCancer</a> <a href="https://journa.host/tags/Therapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Therapy</a> <a href="https://journa.host/tags/ElectricField" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ElectricField</a> <a href="https://journa.host/tags/ClinicalTrial" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ClinicalTrial</a> <a href="https://journa.host/tags/Resection" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Resection</a> <a href="https://journa.host/tags/Surgery" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Surgery</a> <a href="https://journa.host/tags/Ablation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Ablation</a> <a href="https://journa.host/tags/MedicalDevice" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MedicalDevice</a> <a href="https://journa.host/tags/ImmuneSystem" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ImmuneSystem</a> <a href="https://journa.host/tags/BCells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BCells</a> <a href="https://journa.host/tags/TCells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#TCells</a>

DartLabDartLab was happy to play a small role in this just-published study looking at Omicron breakthrough infections. The take-home message is that infections with Omicron after vaccination broaden the existing antibody repertoire. <a href="https://med-mastodon.com/tags/COVID19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#COVID19</a> <a href="https://med-mastodon.com/tags/Bcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Bcells</a> <a href="https://med-mastodon.com/tags/antibody" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#antibody</a> <a href="https://www.nature.com/articles/s41467-023-38345-4" rel="nofollow noopener noreferrer" target="_blank">https://www.nature.com/articles/s41467-023-38345-4</a>

Carolyn Kingimportant new work by @KhaderShabaana lab highlighting the impact of <a href="https://mstdn.science/tags/Bcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Bcells</a> during <a href="https://mstdn.science/tags/Tuberculosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Tuberculosis</a>. best of all - they are crucial players in protection after vaccination/challenge! <a href="https://rdcu.be/c83ty" rel="nofollow noopener noreferrer" target="_blank">https://rdcu.be/c83ty</a>

Carolyn Kingexcited to see this one by Carl Feng &colleagues: <a href="https://doi.org/10.1084/jem.20221392" rel="nofollow noopener noreferrer" target="_blank">https://doi.org/10.1084/jem.20221392</a> <a href="https://mstdn.science/tags/Tuberculosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Tuberculosis</a> <a href="https://mstdn.science/tags/spatial" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#spatial</a> <a href="https://mstdn.science/tags/Bcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Bcells</a>

Chuck DarwinA particular focus is <a href="https://c.im/tags/lymphoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#lymphoid</a> tissues that produce, store and carry <a href="https://c.im/tags/Tcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Tcells</a> that fight infection, and <a href="https://c.im/tags/antibody" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#antibody</a>-making <a href="https://c.im/tags/Bcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Bcells</a>. The coronavirus may also be hiding out in long-lived <a href="https://c.im/tags/nerve" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nerve</a> cells and <a href="https://c.im/tags/heart" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#heart</a> muscle, where it may drive chest <a href="https://c.im/tags/pain" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#pain</a>, brain fog, <a href="https://c.im/tags/fatigue" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#fatigue</a> and other long-Covid symptoms, said Diane Griffin, a virologist at the Johns Hopkins Bloomberg School of Public Health in Baltimore who has studied the body’s response to viral infections for more than 50 years.“We have pretty good information from acute <a href="https://c.im/tags/RNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#RNA</a> <a href="https://c.im/tags/virus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#virus</a> infections that RNA does persist and that it does have consequences,” said Griffin, who is vice president of the US National Academy of Sciences. “Basically, it’s hard to get rid of viruses.” Proving that persistent viral <a href="https://c.im/tags/infection" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#infection</a> causes long Covid will be difficult, Griffin said. Viruses in stealth mode suppress replication to avoid harming their host cells. Despite extensive distribution of coronavirus RNA throughout patients’ bodies, Chertow’s team saw little evidence of inflammation or that the immune system had tried to destroy infected cells outside the respiratory tract.(4/n)<a href="https://www.bloomberg.com/news/features/2023-03-01/hidden-viruses-in-your-body-could-answer-why-long-covid-lingers?leadSource=uverify%20wall" rel="nofollow noopener noreferrer" target="_blank">https://www.bloomberg.com/news/features/2023-03-01/hidden-viruses-in-your-body-could-answer-why-long-covid-lingers?leadSource=uverify%20wall</a>

Carolyn King<a href="https://mstdn.science/tags/Bcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Bcells</a> in human lymphoid structures | Clinical and Experimental Immunology | Oxford Academic<a href="https://academic.oup.com/cei/advance-article/doi/10.1093/cei/uxac101/6825355" rel="nofollow noopener noreferrer" target="_blank">https://academic.oup.com/cei/advance-article/doi/10.1093/cei/uxac101/6825355</a>

Justin J. Taylor PhDMigrating things over from the other social media site, I wanted to share this non-complete list of 200+ papers using fluorescent antigens to assess antigen-specific <a href="https://sciencemastodon.com/tags/Bcells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Bcells</a> by <a href="https://sciencemastodon.com/tags/flowcytometry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#flowcytometry</a>. I tried to cover a lot of labs & antigens, but I've surely missed great work. So please reach out with papers I missed as I plan to keep growing the list and maybe publish the list at some point. Thanks to everyone who helped me compile the list so far! <a href="https://docs.google.com/document/d/1JIeKDAghtgomUlJ7s3gCZCE_kzKyyJPb45ugxEqJbSY/edit" rel="nofollow noopener noreferrer" target="_blank">https://docs.google.com/document/d/1JIeKDAghtgomUlJ7s3gCZCE_kzKyyJPb45ugxEqJbSY/edit</a>

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